Accuracy of 2D shear wave elastography in the diagnosis of liver fibrosis in patients with chronic hepatitis C
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- Tamami Abe
- Division of Hepatology, Department of Internal Medicine Iwate Medical University Morioka Iwate, 020‐8505 Japan
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- Hidekatsu Kuroda
- Division of Hepatology, Department of Internal Medicine Iwate Medical University Morioka Iwate, 020‐8505 Japan
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- Yudai Fujiwara
- Division of Hepatology, Department of Internal Medicine Iwate Medical University Morioka Iwate, 020‐8505 Japan
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- Yuichi Yoshida
- Division of Hepatology, Department of Internal Medicine Iwate Medical University Morioka Iwate, 020‐8505 Japan
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- Akio Miyasaka
- Division of Hepatology, Department of Internal Medicine Iwate Medical University Morioka Iwate, 020‐8505 Japan
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- Naohisa Kamiyama
- Ultrasound General Imaging GE Healthcare Tokyo, 191‐8503 Japan
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- Yasuhiro Takikawa
- Division of Hepatology, Department of Internal Medicine Iwate Medical University Morioka Iwate, 020‐8505 Japan
書誌事項
- 公開日
- 2018-04-06
- 資源種別
- journal article
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/jcu.22592
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>This prospective study was conducted to assess the diagnostic accuracy of two‐dimensional shear wave elastography (2D SWE) in the diagnosis of liver fibrosis in patients with chronic liver disease and hepatitis C virus (HCV) compared with the serum liver fibrosis biomarkers using the results of liver biopsy as the reference standard.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We analyzed 233 consecutive HCV patients. On the same day, 2D SWE m, biochemical tests, and liver biopsy were performed. We used the METAVIR staging system and receiver operating characteristic curves for the analysis.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The success rate of 2D‐SWE was 98.7%. The median shear wave velocities (SWVs) of patients in the F0, F1, F2, F3, and F4 stages were 1.35 m/s, 1.42 m/s, 1.58 m/s, 1.83 m/s, and 2.13 m/s, respectively, demonstrating a stepwise increase (<jats:italic>P</jats:italic> < .0001). The accuracy of 2D‐SWE in the prediction of ≥F1, ≥F2, ≥F3, and F4 was .888 (95% CI: .85‐.93), .915 (95% CI: .88‐095), .940 (95% CI: .91‐.97), and .949 (95% CI: .92‐.97), respectively. 2D‐SWE was significantly superior to serum liver fibrosis biomarkers.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>2D‐SWE was positively correlated with the severity of liver fibrosis and was more useful for to predict all liver fibrosis grades in HCV patients than liver fibrosis biomarkers.</jats:p></jats:sec>
収録刊行物
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- Journal of Clinical Ultrasound
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Journal of Clinical Ultrasound 46 (5), 319-327, 2018-04-06
Wiley
