Magnifying endoscope with <scp>NBI</scp> to predict the depth of invasion in laryngo‐pharyngeal cancer
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- Ichiro Tateya
- Department of Otolaryngology–Head & Neck Surgery Graduate School of Medicine, Kyoto University Kyoto Japan
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- Shuko Morita
- Department of Gastroenterology and Hepatology Graduate School of Medicine, Kyoto University Kyoto Japan
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- Manabu Muto
- Department of Clinical oncology Graduate School of Medicine, Kyoto University Kyoto Japan
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- Shin'ichi Miyamoto
- Department of Gastroenterology and Hepatology Graduate School of Medicine, Kyoto University Kyoto Japan
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- Tomomasa Hayashi
- Department of Clinical oncology Graduate School of Medicine, Kyoto University Kyoto Japan
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- Makiko Funakoshi
- Department of Otolaryngology–Head & Neck Surgery Graduate School of Medicine, Kyoto University Kyoto Japan
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- Ikuo Aoyama
- Department of Otolaryngology–Head & Neck Surgery Graduate School of Medicine, Kyoto University Kyoto Japan
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- Shigeru Hirano
- Department of Otolaryngology–Head & Neck Surgery Graduate School of Medicine, Kyoto University Kyoto Japan
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- Morimasa Kitamura
- Department of Otolaryngology–Head & Neck Surgery Graduate School of Medicine, Kyoto University Kyoto Japan
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- Seiji Ishikawa
- Department of Otolaryngology–Head & Neck Surgery Graduate School of Medicine, Kyoto University Kyoto Japan
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- Yo Kishimoto
- Department of Otolaryngology–Head & Neck Surgery Graduate School of Medicine, Kyoto University Kyoto Japan
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- Mami Morita
- Department of Otolaryngology–Head & Neck Surgery Graduate School of Medicine, Kyoto University Kyoto Japan
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- Patnarin Mahattanasakul
- King ChulalongKorn Memorial Hospital Thailand
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- Satoshi Morita
- Department of Biomedical Statistics and Bioinformatics Graduate School of Medicine, Kyoto University Kyoto Japan
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- Juichi Ito
- Department of Otolaryngology–Head & Neck Surgery Graduate School of Medicine, Kyoto University Kyoto Japan
説明
<jats:sec><jats:title>Objectives/Hypothesis</jats:title><jats:p>To examine if macroscopic classification with a magnifying gastrointestinal endoscope with narrow band imaging (ME‐NBI) is useful in predicting pathological depth of tumor invasion in laryngo‐pharyngeal cancer.</jats:p></jats:sec><jats:sec><jats:title>Study Design</jats:title><jats:p>Retrospective study.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Preoperative endoscopy reports and postoperative pathological reports on 139 laryngo‐pharyngeal cancer lesions were retrospectively reviewed, and the association between macroscopic findings in the lesions and the depth of tumor invasion was analyzed statistically.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The ratios of lesions macroscopically classified as 0‐I (superficial and protruding), 0‐IIa (slightly elevated), 0‐IIb (true flat), 0‐IIc (slightly depressed), and 0‐III (superficial and excavated) in the preoperative endoscopy reports were 3%, 25%, 71%, 1%, and 0%, respectively. Regarding the depth of tumor invasion in the postoperative pathological reports, the ratios of lesions classified as EP (carcinoma in situ), SEP (tumor invades subepithelial layer), and MP (tumor invades muscularis propria) were 73%, 26%, and 1%, respectively. The ratios of subepithelial invasion or muscular invasion in 0‐I, 0‐IIa, and 0‐IIb were 100%, 54%, and 14%, respectively, and showed significant difference (<jats:italic>P</jats:italic> < 0.0001). Only one of 139 lesions invaded the muscular propria.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>This study is the first one to show that macroscopic findings by ME‐NBI predict the depth of tumor invasion in superficial laryngo‐pharyngeal cancer. It was indicated that there is a little chance of muscular invasion if the lesion is endoscopically diagnosed as 0‐I or 0‐II. A new T stage classification based on the depth of tumor invasion may be needed in order to adapt the classification to include transoral surgery.</jats:p></jats:sec><jats:sec><jats:title>Level of Evidence</jats:title><jats:p>4 <jats:italic>Laryngoscope</jats:italic>, 125:1124–1129, 2015</jats:p></jats:sec>
収録刊行物
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- The Laryngoscope
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The Laryngoscope 125 (5), 1124-1129, 2014-11-24
Wiley
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キーワード
詳細情報 詳細情報について
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- CRID
- 1360285705182761856
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- ISSN
- 15314995
- 0023852X
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- データソース種別
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- Crossref
- KAKEN