Akt and PP2A Reciprocally Regulate the Guanine Nucleotide Exchange Factor Dock6 to Control Axon Growth of Sensory Neurons

Yuki Miyamoto

Department of Pharmacology, National Research Institute for Child Health and Development, Setagaya, Tokyo 157-8535, Japan.
Tomohiro Torii

Department of Pharmacology, National Research Institute for Child Health and Development, Setagaya, Tokyo 157-8535, Japan.
Natsuki Yamamori

Department of Pharmacology, National Research Institute for Child Health and Development, Setagaya, Tokyo 157-8535, Japan.
Toru Ogata

Department of Biological Sciences, Tokyo Institute of Technology, Midori, Yokohama 226-8501, Japan.
Akito Tanoue

Department of Pharmacology, National Research Institute for Child Health and Development, Setagaya, Tokyo 157-8535, Japan.
Junji Yamauchi

Department of Pharmacology, National Research Institute for Child Health and Development, Setagaya, Tokyo 157-8535, Japan.

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<jats:p>The phosphorylation status of Dock6 causes sensory neuron axons to switch from extension to branching.</jats:p>

Science Signaling

Science Signaling 6 (265), ra15-, 2013-03-05

American Association for the Advancement of Science (AAAS)