Purinergic P2Y <sub>6</sub> receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II–induced hypertension

DOI Web Site 被引用文献19件 参考文献57件 オープンアクセス
  • Akiyuki Nishimura
    Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Aichi 444-8787, Japan.
  • Caroline Sunggip
    Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Aichi 444-8787, Japan.
  • Hidetoshi Tozaki-Saitoh
    Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
  • Tsukasa Shimauchi
    Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Aichi 444-8787, Japan.
  • Takuro Numaga-Tomita
    Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Aichi 444-8787, Japan.
  • Katsuya Hirano
    Department of Cardiovascular Physiology, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan.
  • Tomomi Ide
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
  • Jean-Marie Boeynaems
    Institute of Interdisciplinary Research, School of Medicine, Université Libre de Bruxelles, Gosselies 6041, Belgium.
  • Hitoshi Kurose
    Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
  • Makoto Tsuda
    Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
  • Bernard Robaye
    Institute of Interdisciplinary Research, School of Medicine, Université Libre de Bruxelles, Gosselies 6041, Belgium.
  • Kazuhide Inoue
    Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
  • Motohiro Nishida
    Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Aichi 444-8787, Japan.

抄録

<jats:p>Aging changes the response of blood vessels to angiotensin II, contributing to hypertension.</jats:p>

収録刊行物

  • Science Signaling

    Science Signaling 9 (411), ra7-, 2016-01-19

    American Association for the Advancement of Science (AAAS)

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