PUB4, a CERK1-Interacting Ubiquitin Ligase, Positively Regulates MAMP-Triggered Immunity in Arabidopsis
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- Yoshitake Desaki
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Shohei Takahashi
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Kenta Sato
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Kanako Maeda
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Saki Matsui
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Ikuya Yoshimi
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Takaki Miura
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Jun-Ichi Jumonji
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Jun Takeda
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Kohei Yashima
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Masaki Kohari
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Takayoshi Suenaga
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Hayato Terada
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Tomoko Narisawa
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Takeo Shimizu
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Emi Yumoto
- Advanced Instrumental Analysis Center, Teikyo University, Utsunomiya, Tochigi, Japan
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- Koji Miyamoto
- Department of Biosciences, Faculty of Science and Engineering, Teikyo University, Utsunomiya, Tochigi, Japan
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- Mari Narusaka
- Okayama Prefectural Technology Center for Agriculture, Forestry, and Fisheries, Research Institute for Biological Sciences, Okayama, Japan
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- Yoshihiro Narusaka
- Okayama Prefectural Technology Center for Agriculture, Forestry, and Fisheries, Research Institute for Biological Sciences, Okayama, Japan
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- Hanae Kaku
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
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- Naoto Shibuya
- Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
抄録
<jats:title>Abstract</jats:title> <jats:p>Lysin motif (LysM) receptor-like kinase CERK1 is a co-receptor essential for plant immune responses against carbohydrate microbe-associated molecular patterns (MAMPs). Concerning the immediate downstream signaling components of CERK1, receptor-like cytoplasmic kinases such as PBL27 and other RLCK VII members have been reported to regulate immune responses positively. In this study, we report that a novel CERK1-interacting E3 ubiquitin ligase, PUB4, is also involved in the regulation of MAMP-triggered immune responses. Knockout of PUB4 resulted in the alteration of chitin-induced defense responses, indicating that PUB4 positively regulates reactive oxygen species generation and callose deposition but negatively regulates MAPK activation and defense gene expression. On the other hand, detailed analyses of a double knockout mutant of pub4 and sid2, a mutant of salicylic acid (SA) synthesis pathway, showed that the contradictory phenotype of the pub4 mutant was actually caused by abnormal accumulation of SA in this mutant and that PUB4 is a positive regulator of immune responses. The present and recent findings on the role of PUB4 indicate that PUB4 is a unique E3 ubiquitin ligase involved in the regulation of both plant immunity and growth/development.</jats:p>
収録刊行物
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- Plant and Cell Physiology
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Plant and Cell Physiology 60 (11), 2573-2583, 2019-08-01
Oxford University Press (OUP)
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詳細情報 詳細情報について
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- CRID
- 1360286994660290048
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- ISSN
- 14719053
- 00320781
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- データソース種別
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- Crossref
- KAKEN