Risk factors associated with the development of aspiration pneumonia in patients receiving radiotherapy for head and neck cancer: retrospective study
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- Yumiko Kawashita
- Oral Care Center, Nagasaki University Hospital Nagasaki Japan
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- Shimpei Morimoto
- Innovation Platform and Office for Precision Medicine Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
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- Kensuke Tashiro
- Department of Oral Health Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
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- Sakiko Soutome
- Oral Care Center, Nagasaki University Hospital Nagasaki Japan
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- Masako Yoshimatsu
- Oral Care Center, Nagasaki University Hospital Nagasaki Japan
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- Noriko Nakao
- Oral Care Center, Nagasaki University Hospital Nagasaki Japan
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- Tadafumi Kurogi
- Oral Care Center, Nagasaki University Hospital Nagasaki Japan
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- Thoshiyuki Saito
- Department of Oral Health Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
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- Takashi Ukai
- Oral Care Center, Nagasaki University Hospital Nagasaki Japan
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- Masahiro Umeda
- Department of Clinical Oral Oncology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
説明
<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Patients with head and neck cancer who are receiving radiotherapy can develop aspiration pneumonia. Determination of the incidence of aspiration pneumonia and the associated risk factors could facilitate the identification of high‐risk patients.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>In this retrospective study, we determined the incidence of aspiration pneumonia in 357 patients receiving radiotherapy along with oral care for head and neck cancer. We also performed univariate and multivariable logistic regression analyses to investigate the risk factors for this complication.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The incidence of aspiration pneumonia was 17.6%. Hypopharyngeal cancer, grade 3 oral mucositis, and nasogastric tube feeding were independent risk factors. Moreover, the development of aspiration pneumonia was one of the major effects on the discontinuation of radiotherapy.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Approximately, one‐sixth of the patients developed aspiration pneumonia despite appropriate oral care during radiotherapy for head and neck cancer. Aspiration pneumonia during radiotherapy could adversely affect head and neck cancer management.</jats:p></jats:sec>
収録刊行物
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- Head & Neck
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Head & Neck 42 (9), 2571-2580, 2020-06
Wiley
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詳細情報 詳細情報について
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- CRID
- 1360290617630950016
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- ISSN
- 10970347
- 10433074
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- データソース種別
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- Crossref
- KAKEN