A fully synthetic 6-aza-artemisinin bearing an amphiphilic chain generates aggregates and exhibits anti-cancer activities
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- Hikari Koi
- Department of Applied Chemistry
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- Norihito Takahashi
- Department of Applied Chemistry
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- Yasufumi Fuchi
- Faculty of Pharmaceutical Sciences
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- Tomohiro Umeno
- Faculty of Pharmaceutical Sciences
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- Yukiko Muramatsu
- Division of Molecular Biotherapy
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- Hiroyuki Seimiya
- Division of Molecular Biotherapy
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- Satoru Karasawa
- Faculty of Pharmaceutical Sciences
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- Hiroki Oguri
- Department of Chemistry
説明
<p>Appendage of an amphiphilic chain by exploiting the nitrogen installed on the 6-aza-artemisinin imparted self-assembling properties. The fully synthetic 6-aza-artemisinin formed aggregates and exhibited increased <italic>in vitro</italic> anti-cancer activities.</p>
収録刊行物
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- Organic & Biomolecular Chemistry
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Organic & Biomolecular Chemistry 18 (28), 5339-5343, 2020
Royal Society of Chemistry (RSC)
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詳細情報 詳細情報について
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- CRID
- 1360290617825833856
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- ISSN
- 14770539
- 14770520
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- データソース種別
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- Crossref
- KAKEN