The Dipeptidyl Peptidase IV Inhibitor Vildagliptin Suppresses Endogenous Glucose Production and Enhances Islet Function after Single-Dose Administration in Type 2 Diabetic Patients

  • Bogdan Balas
    Division of Diabetes (B.B., M.R.B., C.D., K.C., R.A.D.), Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229
  • Muhammad R. Baig
    Division of Diabetes (B.B., M.R.B., C.D., K.C., R.A.D.), Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229
  • Catherine Watson
    Novartis Institutes for Biomedical Research (C.W., Y.-L.H.), Cambridge, Massachusetts 02139
  • Beth E. Dunning
    PharmaWrite, L.L.C. (B.E.D.), Princeton, New Jersey 08540
  • Monica Ligueros-Saylan
    Novartis Pharmaceuticals Corp. (M.L.-S., Y.W., J.E.F.), East Hanover, New Jersey 07054
  • Yibin Wang
    Novartis Pharmaceuticals Corp. (M.L.-S., Y.W., J.E.F.), East Hanover, New Jersey 07054
  • Yan-Ling He
    Novartis Institutes for Biomedical Research (C.W., Y.-L.H.), Cambridge, Massachusetts 02139
  • Celia Darland
    Division of Diabetes (B.B., M.R.B., C.D., K.C., R.A.D.), Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229
  • Jens J. Holst
    Panum Institute (J.J.H., C.F.D.), University of Copenhagen, DK-2400 Copenhagen, Denmark
  • Carolyn F. Deacon
    Panum Institute (J.J.H., C.F.D.), University of Copenhagen, DK-2400 Copenhagen, Denmark
  • Kenneth Cusi
    Division of Diabetes (B.B., M.R.B., C.D., K.C., R.A.D.), Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229
  • Andrea Mari
    Institute of Biomedical Engineering (A.M.), National Research Council, 35127 Padova, Italy
  • James E. Foley
    Novartis Pharmaceuticals Corp. (M.L.-S., Y.W., J.E.F.), East Hanover, New Jersey 07054
  • Ralph A. DeFronzo
    Division of Diabetes (B.B., M.R.B., C.D., K.C., R.A.D.), Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229

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