Comorbid and inflammatory characteristics of genetic subtypes of clonal hematopoiesis
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- Elina K. Cook
- Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada;
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- Terumi Izukawa
- Baycrest Health Sciences, Toronto, ON, Canada;
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- Sherylan Young
- Department of Family and Community Medicine,
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- Gili Rosen
- Baycrest Health Sciences, Toronto, ON, Canada;
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- Mina Jamali
- Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; and
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- Liying Zhang
- Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; and
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- Dylan Johnson
- Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada;
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- Eva Bain
- Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada;
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- Jamie Hilland
- Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada;
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- Christina K. Ferrone
- Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada;
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- Jonah Buckstein
- Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada;
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- Janika Francis
- Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; and
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- Bushra Momtaz
- Baycrest Health Sciences, Toronto, ON, Canada;
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- Amy J. M. McNaughton
- Department of Psychiatry, and
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- Xudong Liu
- Department of Psychiatry, and
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- Brooke Snetsinger
- Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada;
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- Rena Buckstein
- Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; and
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- Michael J. Rauh
- Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada;
説明
<jats:title>Key Points</jats:title> <jats:p>CH may be associated with broader ill health (worse performance status, increased and potentially novel comorbidities). Serum interleukin-6 is elevated in people with CH and genetic subtypes, providing a view of the human systemic inflammatory landscape of CH.</jats:p>
収録刊行物
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- Blood Advances
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Blood Advances 3 (16), 2482-2486, 2019-08-21
American Society of Hematology
