Synovial fibroblasts in 2017

  • Caroline Ospelt
    Department of Rheumatology, Center of Experimental Rheumatology, University Hospital and University of Zurich, Zurich, Switzerland

書誌事項

公開日
2017-10
DOI
  • 10.1136/rmdopen-2017-000471
公開者
BMJ

説明

<jats:p>Stromal cells like synovial fibroblasts gained great interest over the years, since it has become clear that they strongly influence their environment and neighbouring cells. The current review describes the role of synovial fibroblasts as cells of the innate immune system and expands on their involvement in inflammation and cartilage destruction in rheumatoid arthritis (RA). Furthermore, epigenetic changes in RA synovial fibroblasts and studies that focused on the identification of different subsets of synovial fibroblasts are discussed.</jats:p>

収録刊行物

  • RMD Open

    RMD Open 3 (2), e000471-, 2017-10

    BMJ

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