Hearing Impairment and Incident Dementia: Findings from the English Longitudinal Study of Ageing
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- Hilary R. Davies
- Institute of Epidemiology and Public Health University College London London United Kingdom
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- Dorina Cadar
- Institute of Epidemiology and Public Health University College London London United Kingdom
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- Annie Herbert
- Institute of Epidemiology and Public Health University College London London United Kingdom
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- Martin Orrell
- Institute of Mental Health University of Nottingham Nottingham United Kingdom
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- Andrew Steptoe
- Institute of Epidemiology and Public Health University College London London United Kingdom
Description
<jats:sec><jats:title>Objectives</jats:title><jats:p>To determine whether hearing loss is associated with incident physician‐diagnosed dementia in a representative sample.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>Retrospective cohort study.</jats:p></jats:sec><jats:sec><jats:title>Setting</jats:title><jats:p>English Longitudinal Study of Ageing.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>Adults aged 50 and older.</jats:p></jats:sec><jats:sec><jats:title>Measurements</jats:title><jats:p>Cross‐sectional associations between self‐reported (n = 7,865) and objective hearing measures (n = 6,902) and dementia were examined using multinomial‐logistic regression. The longitudinal association between self‐reported hearing at Wave 2 (2004/05) and cumulative physician‐diagnosed dementia up to Wave 7 (2014/15) was modelled using Cox proportional hazards regression.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>After adjustment for potential confounders, in cross‐sectional analysis, participants who had self‐reported or objective moderate and poor hearing were more likely to have a dementia diagnosis than those with normal hearing (self‐reported: odds ratio <jats:styled-content style="fixed-case">OR</jats:styled-content> = 1.6, 95% <jats:styled-content style="fixed-case">CI</jats:styled-content> = 1.1–2.4 moderate hearing; <jats:styled-content style="fixed-case">OR</jats:styled-content> = 2.6, 95% <jats:styled-content style="fixed-case">CI</jats:styled-content> = 1.7–3.9 poor hearing, objective: <jats:styled-content style="fixed-case">OR</jats:styled-content> = 1.6, 95% <jats:styled-content style="fixed-case">CI</jats:styled-content> = 1.0–2.8 moderate hearing; <jats:styled-content style="fixed-case">OR</jats:styled-content> = 4.4, 95% <jats:styled-content style="fixed-case">CI</jats:styled-content> = 1.9–9.9 poor hearing). Longitudinally, the hazard of developing dementia was 1.4 (95% <jats:styled-content style="fixed-case">CI</jats:styled-content> = 1.0–1.9) times as high in individuals who reported moderate hearing and 1.6 (95% <jats:styled-content style="fixed-case">CI</jats:styled-content> = 1.1–2.0) times as high in those who reported poor hearing.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Older adults with hearing loss are at greater risk of dementia than those with normal hearing. These findings are consistent with the rationale that correction of hearing loss could help delay the onset of dementia, or that hearing loss itself could serve as a risk indicator for cognitive decline.</jats:p></jats:sec>
Journal
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- Journal of the American Geriatrics Society
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Journal of the American Geriatrics Society 65 (9), 2074-2081, 2017-07-22
Wiley
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Details 詳細情報について
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- CRID
- 1360292620198474880
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- ISSN
- 15325415
- 00028614
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- Data Source
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- Crossref