The Akt1-eNOS Axis Illustrates the Specificity of Kinase-Substrate Relationships in Vivo

  • Michael Schleicher
    Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Jun Yu
    Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Takahisa Murata
    Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
  • Berhad Derakhshan
    Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Dimitriy Atochin
    Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, MA 02129, USA.
  • Li Qian
    Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, MA 02129, USA.
  • Satoshi Kashiwagi
    Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, MA 02129, USA.
  • Annarita Di Lorenzo
    Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Kenneth D. Harrison
    Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Paul L. Huang
    Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, MA 02129, USA.
  • William C. Sessa
    Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.

説明

<jats:p>Akt mediates postnatal angiogenesis through eNOS signaling.</jats:p>

収録刊行物

  • Science Signaling

    Science Signaling 2 (82), ra41-, 2009-08-04

    American Association for the Advancement of Science (AAAS)

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