Preparation of quinazoline derivatives through ring‐closure of aromatic <i>ortho</i>‐cyano‐acylamino compounds in alkaline alcoholic or phenolic medium. I. 4‐RO‐substituted quinazolines

K. W. Breukink, L. H. Krol, P. E. Verkade, B. M. Wepster

doi:10.1002/recl.19570760505

Preparation of quinazoline derivatives through ring‐closure of aromatic <i>ortho</i>‐cyano‐acylamino compounds in alkaline alcoholic or phenolic medium. I. 4‐RO‐substituted quinazolines

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<jats:title>Abstract</jats:title><jats:p>On boiling aromatic <jats:italic>ortho</jats:italic>‐cyano‐acylamino compounds in alkaline alcoholic or phenolic solution ‐ medium ROH ‐ 4‐RO‐substituted quinazolines are formed. Some examples of this reaction are described.</jats:p>