Detection of Suppression of Bitterness by Sweet Substance Using a Multichannel Taste Sensor
説明
A multichannel taste sensor whose transducer is composed of several kinds of lipid/polymer membranes with different characteristics can detect taste in a manner similar to human gustatory sensation. Taste information is transformed into a pattern composed of electric signals of membrane potentials of the receptor part. In the present study, it was shown that the suppression of the bitterness of quinine and a drug substance by sucrose can be quantified using a multichannel taste sensor. The present method can be expected to provide a new automated method to measure the strength of bitterness of drug substance in the place of sensory evaluation.
収録刊行物
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- Journal of Pharmaceutical Sciences
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Journal of Pharmaceutical Sciences 87 (5), 552-555, 1998-05
American Geophysical Union (AGU)