3D Bioprinting of Tissue/Organ Models
-
- Falguni Pati
- Division of Proteomics and Nanobiotechnology, Science for Life Laboratory KTH-Royal Institute of Technology Stockholm Sweden
-
- Jesper Gantelius
- Division of Proteomics and Nanobiotechnology, Science for Life Laboratory KTH-Royal Institute of Technology Stockholm Sweden
-
- Helene Andersson Svahn
- Division of Proteomics and Nanobiotechnology, Science for Life Laboratory KTH-Royal Institute of Technology Stockholm Sweden
Description
<jats:title>Abstract</jats:title><jats:p>In vitro tissue/organ models are useful platforms that can facilitate systematic, repetitive, and quantitative investigations of drugs/chemicals. The primary objective when developing tissue/organ models is to reproduce physiologically relevant functions that typically require complex culture systems. Bioprinting offers exciting prospects for constructing 3D tissue/organ models, as it enables the reproducible, automated production of complex living tissues. Bioprinted tissues/organs may prove useful for screening novel compounds or predicting toxicity, as the spatial and chemical complexity inherent to native tissues/organs can be recreated. In this Review, we highlight the importance of developing 3D in vitro tissue/organ models by 3D bioprinting techniques, characterization of these models for evaluating their resemblance to native tissue, and their application in the prioritization of lead candidates, toxicity testing, and as disease/tumor models.</jats:p>
Journal
-
- Angewandte Chemie International Edition
-
Angewandte Chemie International Edition 55 (15), 4650-4665, 2016-02-19
Wiley
- Tweet
Details 詳細情報について
-
- CRID
- 1360292620800914432
-
- ISSN
- 15213773
- 14337851
-
- Data Source
-
- Crossref