Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing
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- Ti-Hsuan Ku
- Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA 92093-0407, USA
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- Tiantian Zhang
- Materials Science and Engineering Program, University of California San Diego, La Jolla, CA 92093-0418, USA
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- Hua Luo
- Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA 92093-0407, USA
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- Tony Yen
- Department of Bioengineering, University of California San Diego, La Jolla, CA 92093-0412, USA
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- Ping-Wei Chen
- Chemical Engineering Program, University of California San Diego, La Jolla, CA 92093-0448, USA
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- Yuanyuan Han
- Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA 92093-0407, USA
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- Yu-Hwa Lo
- Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA 92093-0407, USA
書誌事項
- 公開日
- 2015-07-06
- 権利情報
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- https://creativecommons.org/licenses/by/4.0/
- DOI
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- 10.3390/s150716281
- 公開者
- MDPI AG
説明
<jats:p>Detection of small molecules or proteins of living cells provides an exceptional opportunity to study genetic variations and functions, cellular behaviors, and various diseases including cancer and microbial infections. Our aim in this review is to give an overview of selected research activities related to nucleic acid-based aptamer techniques that have been reported in the past two decades. Limitations of aptamers and possible approaches to overcome these limitations are also discussed.</jats:p>
収録刊行物
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- Sensors
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Sensors 15 (7), 16281-16313, 2015-07-06
MDPI AG