High speed intravascular photoacoustic imaging with fast optical parametric oscillator laser at 1.7 <i>μ</i>m
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- Zhonglie Piao
- University of California 1 Beckman Laser Institute, Department of Biomedical Engineering, , Irvine, Irvine, California 92612, USA
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- Teng Ma
- University of Southern California 3 Department of Biomedical Engineering, NIH Ultrasonic Transducer Resource Center, , Los Angeles, California 90089, USA
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- Jiawen Li
- University of California 1 Beckman Laser Institute, Department of Biomedical Engineering, , Irvine, Irvine, California 92612, USA
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- Maximilian T. Wiedmann
- University of California 1 Beckman Laser Institute, Department of Biomedical Engineering, , Irvine, Irvine, California 92612, USA
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- Shenghai Huang
- University of California 1 Beckman Laser Institute, Department of Biomedical Engineering, , Irvine, Irvine, California 92612, USA
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- Mingyue Yu
- University of Southern California 3 Department of Biomedical Engineering, NIH Ultrasonic Transducer Resource Center, , Los Angeles, California 90089, USA
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- K. Kirk Shung
- University of Southern California 3 Department of Biomedical Engineering, NIH Ultrasonic Transducer Resource Center, , Los Angeles, California 90089, USA
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- Qifa Zhou
- University of Southern California 3 Department of Biomedical Engineering, NIH Ultrasonic Transducer Resource Center, , Los Angeles, California 90089, USA
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- Chang-Seok Kim
- Pusan National University 2 Department of Cogno-Mechatronics Engineering, , Busan 609-735, South Korea
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- Zhongping Chen
- University of California 1 Beckman Laser Institute, Department of Biomedical Engineering, , Irvine, Irvine, California 92612, USA
抄録
<jats:p>Intravascular photoacoustic imaging at 1.7 μm spectral band has shown promising capabilities for lipid-rich vulnerable atherosclerotic plaque detection. In this work, we report a high speed catheter-based integrated intravascular photoacoustic/intravascular ultrasound (IVPA/IVUS) imaging system with a 500 Hz optical parametric oscillator laser at 1725 nm. A lipid-mimicking phantom and atherosclerotic rabbit abdominal aorta were imaged at 1 frame per second, which is two orders of magnitude faster than previously reported in IVPA imaging with the same wavelength. Clear photoacoustic signals by the absorption of lipid rich deposition demonstrated the ability of the system for high speed vulnerable atherosclerotic plaques detection.</jats:p>
収録刊行物
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- Applied Physics Letters
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Applied Physics Letters 107 (8), 2015-08-24
AIP Publishing
