Cloning of the <i>Arabidopsis</i> Clock Gene <i>TOC1</i> , an Autoregulatory Response Regulator Homolog

DOI Web Site 被引用文献84件
  • Carl Strayer
    Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Tokitaka Oyama
    Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Thomas F. Schultz
    Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Ramanujam Raman
    Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • David E. Somers
    Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Paloma Más
    Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Satchidananda Panda
    Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Joel A. Kreps
    Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Steve A. Kay
    Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.

抄録

<jats:p> The <jats:italic>toc1</jats:italic> mutation causes shortened circadian rhythms in light-grown <jats:italic>Arabidopsis</jats:italic> plants. Here, we report the same <jats:italic>toc1</jats:italic> effect in the absence of light input to the clock. We also show that <jats:italic>TOC1</jats:italic> controls photoperiodic flowering response through clock function. The <jats:italic>TOC1</jats:italic> gene was isolated and found to encode a nuclear protein containing an atypical response regulator receiver domain and two motifs that suggest a role in transcriptional regulation: a basic motif conserved within the <jats:italic>CONSTANS</jats:italic> family of transcription factors and an acidic domain. <jats:italic>TOC1</jats:italic> is itself circadianly regulated and participates in a feedback loop to control its own expression. </jats:p>

収録刊行物

  • Science

    Science 289 (5480), 768-771, 2000-08-04

    American Association for the Advancement of Science (AAAS)

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