Peptide Bond Formation of Amino Acids by Transient Masking with Silylating Reagents

  • Wataru Muramatsu
    Molecular Catalyst Research Center, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan
  • Hisashi Yamamoto
    Molecular Catalyst Research Center, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan

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Description

A one-pot peptide bond-forming reaction has been developed using unprotected amino acids and peptides. Two different silylating reagents, HSi[OCH(CF

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