Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface

DOI Web Site 1 Citations
  • Sankalp Malhotra
    Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA
  • Don Hayes
    The Ohio State University College of Medicine, Columbus, Ohio, USA
  • Daniel J. Wozniak
    The Ohio State University College of Medicine, Columbus, Ohio, USA

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<jats:p>In human pathophysiology, the clash between microbial infection and host immunity contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this phenomenon, wherein a dysfunctional, hyperinflammatory immune response combined with chronic pulmonary infections wreak havoc upon the airway, leading to a disease course of substantial morbidity and shortened life span.</jats:p>

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