Early recovery following new onset anosmia during the COVID-19 pandemic – an observational cohort study

<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>A rapidly evolving evidence suggests that smell and taste disturbance are common symptoms in COVID-19 infection. As yet there are no reports on duration and recovery rates. We set out to characterise patients reporting new onset smell and taste disturbance during the COVID-19 pandemic and report on early recovery rates.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Online Survey of patients reporting self-diagnosed new onset smell and taste disturbance during the COVID-19 pandemic, with 1 week follow-up.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Three hundred eighty-two patents completed bot an initial and follow-up survey. 86.4% reported complete anosmia and a further 11.5% a very severe loss of smell at the time of completing the first survey. At follow-up 1 week later, there is already significant improvement in self-rating of severity of olfactory loss. 80.1% report lower severity scores at follow-up, 17.6% are unchanged and 1.9% are worse. 11.5% already report compete resolution at follow up, while 17.3% report persistent complete loss of smell, with reported duration being 1 to over 4 weeks. This is reflected in the overall cumulative improvement rate of 79% patients overall in the interval between surveys.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>A review of the growing evidence base supports the likelihood that out cohort have suffered olfactory loss as part of COVID-19 infection. While early recovery rates are encouraging, long term rates will need to be further investigated and there may be an increase in patients with persistent post-viral loss as a result of the pandemic.</jats:p><jats:p>We further call for loss of sense of smell to be formerly recognised as a marker of COVID-19 infection.</jats:p></jats:sec>