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- Nathan Fraikin
- Cellular and Molecular Microbiology (CM2), Faculté des Sciences, Université Libre de Bruxelles, Gosselies, Belgium
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- Frédéric Goormaghtigh
- Research Area Infection Biology, Biozentrum, University of Basel, Basel, Switzerland
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- Laurence Van Melderen
- Cellular and Molecular Microbiology (CM2), Faculté des Sciences, Université Libre de Bruxelles, Gosselies, Belgium
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- William Margolin
- editor
説明
<jats:p>Type II toxin-antitoxin (TA) systems are small genetic elements composed of a toxic protein and its cognate antitoxin protein, the latter counteracting the toxicity of the former. While TA systems were initially discovered on plasmids, functioning as addiction modules through a phenomenon called postsegregational killing, they were later shown to be massively present in bacterial chromosomes, often in association with mobile genetic elements. Extensive research has been conducted in recent decades to better understand the physiological roles of these chromosomally encoded modules and to characterize the conditions leading to their activation.</jats:p>
収録刊行物
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- Journal of Bacteriology
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Journal of Bacteriology 202 (7), 00763-, 2020-03-11
American Society for Microbiology
