Toward an understanding of regulatory T cells in COVID‐19: A systematic review
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- Mahsa Rahimzadeh
- Infectious and Tropical Diseases Research Center, Hormozgan Health Institute Hormozgan University of Medical Sciences Bandar Abbas Iran
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- Nadereh Naderi
- Department of Immunology, Faculty of Medicine Hormozgan University of Medical Sciences Bandar Abbas Iran
書誌事項
- 公開日
- 2021-04
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/jmv.26891
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>A more detailed understanding of Treg cells in COVID‐19 infection will broaden our knowledge of the COVID‐19 immunopathology and give us more insight into the curative immune‐based strategies. We systematically searched electronic databases (PubMed, Google Scholar, EMBASE) and identified 18 eligible studies. Despite the inconsistencies between the results, we observed a trend toward decreasing Treg levels in severe COVID‐19 patients. This finding underlines the hypothesis that Tregs play a role in the pathogenesis of COVID‐19. Further studies on Tregs' functional aspects are necessary to illustrate Tregs' potential role in COVID‐19 disease.</jats:p>
収録刊行物
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- Journal of Medical Virology
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Journal of Medical Virology 93 (7), 4167-4181, 2021-04
Wiley