Potential Role of Inorganic Confined Environments in Prebiotic Phosphorylation

DOI Web Site 5 Citations
  • Avinash Dass
    Centre de Biophysique Moléculaire (CBM), Centre National de la Recherche Scientifique (CNRS), Rue Charles Sadron, 45071 Orléans, France
  • Maguy Jaber
    Laboratoire d’Archelologie Moléculaire et Structurale, Sorbonne Universités, UPMC Paris 06, CNRS UMR 8220, 4 place Jussieu, F-75005 Paris, France
  • André Brack
    Centre de Biophysique Moléculaire (CBM), Centre National de la Recherche Scientifique (CNRS), Rue Charles Sadron, 45071 Orléans, France
  • Frédéric Foucher
    Centre de Biophysique Moléculaire (CBM), Centre National de la Recherche Scientifique (CNRS), Rue Charles Sadron, 45071 Orléans, France
  • Terence Kee
    School of Chemistry, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, UK
  • Thomas Georgelin
    Centre de Biophysique Moléculaire (CBM), Centre National de la Recherche Scientifique (CNRS), Rue Charles Sadron, 45071 Orléans, France
  • Frances Westall
    Centre de Biophysique Moléculaire (CBM), Centre National de la Recherche Scientifique (CNRS), Rue Charles Sadron, 45071 Orléans, France

Description

<jats:p>A concise outlook on the potential role of confinement in phosphorylation and phosphate condensation pertaining to prebiotic chemistry is presented. Inorganic confinement is a relatively uncharted domain in studies concerning prebiotic chemistry, and even more so in terms of experimentation. However, molecular crowding within confined dimensions is central to the functioning of contemporary biology. There are numerous advantages to confined environments and an attempt to highlight this fact, within this article, has been undertaken, keeping in context the limitations of aqueous phase chemistry in phosphorylation and, to a certain extent, traditional approaches in prebiotic chemistry.</jats:p>

Journal

  • Life

    Life 8 (1), 7-, 2018-03-05

    MDPI AG

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