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- P. A. Nistor
- Regenerative Medicine Laboratory, University of Bristol, Bristol BS8 1TD, UK
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- P. W. May
- School of Chemistry, University of Bristol, Bristol BS8 1TS, UK
書誌事項
- 公開日
- 2017-09
- 権利情報
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- https://royalsociety.org/journals/ethics-policies/data-sharing-mining/
- DOI
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- 10.1098/rsif.2017.0382
- 公開者
- The Royal Society
この論文をさがす
説明
<jats:p> Progress made in the last two decades in chemical vapour deposition technology has enabled the production of inexpensive, high-quality coatings made from diamond to become a scientific and commercial reality. Two properties of diamond make it a highly desirable candidate material for biomedical applications: first, it is bioinert, meaning that there is minimal immune response when diamond is implanted into the body, and second, its electrical conductivity can be altered in a controlled manner, from insulating to near-metallic. <jats:italic>In vitro,</jats:italic> diamond can be used as a substrate upon which a range of biological cells can be cultured. <jats:italic>In vivo</jats:italic> , diamond thin films have been proposed as coatings for implants and prostheses. Here, we review a large body of data regarding the use of diamond substrates for <jats:italic>in vitro</jats:italic> cell culture. We also detail more recent work exploring diamond-coated implants with the main targets being bone and neural tissue. We conclude that diamond emerges as one of the major new biomaterials of the twenty-first century that could shape the way medical treatment will be performed, especially when invasive procedures are required. </jats:p>
収録刊行物
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- Journal of The Royal Society Interface
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Journal of The Royal Society Interface 14 (134), 20170382-, 2017-09
The Royal Society