<jats:sec><jats:title>Objectives/Hypothesis</jats:title><jats:p>Arytenoid adduction (AA) has been indicated for unilateral vocal fold paralysis (UVFP) patients with vertical vocal fold height mismatch and/or large posterior glottic gaps that are unable to be adequately addressed by anterior medialization techniques. Although AA offers several advantages over other methods, it is technically challenging and involves significant laryngeal manipulation of the cricoarytenoid joint. A novel, minimally invasive endoscopic arytenoid medialization technique is presented for the closure of the posterior commissure.</jats:p></jats:sec><jats:sec><jats:title>Study Design</jats:title><jats:p>Prospective case series.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Seventeen consecutive patients were diagnosed and treated with unilateral endoscopic arytenoid medialization (EAM) combined with injection laryngoplasty because of unilateral vocal fold paralysis. Jitter, shimmer, harmonics‐to‐noise ratio (HNR), maximum phonation time (MPT), fundamental frequency (F<jats:sub>0</jats:sub>), Voice Handicap Index (VHI), peak inspiratory flow (PIF), and quality of life (QoL) were evaluated preoperatively, 1 month, and 1 year after EAM.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Jitter, shimmer, HNR, and MPT significantly improved and remained stable 1 year after the intervention. F<jats:sub>0</jats:sub> and PIF remained unchanged. Significant improvements in VHI and QoL demonstrated patient satisfaction with voicing and respiratory functions.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Endoscopic arytenoid medialization is a quick, minimally invasive solution for unilateral vocal fold paralysis. With simultaneous augmentation of the vocal fold, it provides a complete glottic closure along the entire vocal fold in UVFP patients.</jats:p></jats:sec><jats:sec><jats:title>Level of Evidence</jats:title><jats:p>4 <jats:italic>Laryngoscope</jats:italic>, 131:E903–E910, 2021</jats:p></jats:sec>