-
- Tiziana Ciarambino
- Department of Internal Medicine, Marcianise Hospital, ASL Caserta, Italy
-
- Ombretta Para
- Department of Internal Medicine, Careggi Hospital, University of Florence, Florence, Italy
-
- Mauro Giordano
- Department of Internal Medicine, University of Campania, L. Vanvitelli, Naples, Italy
説明
<jats:p> In COVID-19 disease, are reported gender differences in relation to severity and death. The aim of this review is to highlight gender differences in the immune response to COVID-19. The included studies were identified using PubMed, until 30 October 2020. The search included the following keywords: SARS-CoV-2, COVID-19, gender, age, sex, and immune system. Literature described that females compared to males have greater inflammatory, antiviral, and humoral immune responses. In female, estrogen is a potential ally to alleviate SARS-COV-2 disease. In male, testosterone reduces vaccination response and depresses the cytokine response. In the older patients, and in particular, in female older patients, it has been reported a progressive functional decline in the immune systems. Differences by gender were reported in infection diseases, including SARS-CoV-2. These data should be confirmed by the other epidemiological studies. </jats:p>
収録刊行物
-
- Women's Health
-
Women's Health 17 174550652110222-, 2021-01
SAGE Publications
