Chemical and Bioactive Marine Natural Products of Coral-Derived Microorganisms (2015-2017)
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- Xue-Mei Hou
- Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
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- Yang Hai
- Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
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- Yu-Cheng Gu
- Syngenta Jealott’s Hill International Research Centre, Bracknell RG42 6EY, Berkshire, United Kingdom
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- Chang-Yun Wang
- Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
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- Chang-Lun Shao
- Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
抄録
<jats:sec> <jats:title>:</jats:title> <jats:p>Coral-derived microorganisms are known for their inherent ability to produce novel products of pharmaceutical importance. Nearly 260 marine natural products (MNPs) have been isolated from coral-derived microorganisms till 2014. In the last three years, 118 MNPs have been isolated from coral-associated microorganisms including 46 new compounds, two with a novel skeleton, and four new natural products. Most of them exhibited in vitro or in vivo activities against tumor cell lines, parasites, pathogenic bacteria, fungi and virus. We reviewed the natural products reported from 2015 to 2017 that have a wide range of bioactivities against different biological targets.</jats:p> </jats:sec>
収録刊行物
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- Current Medicinal Chemistry
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Current Medicinal Chemistry 26 (38), 6930-6941, 2019-01-03
Bentham Science Publishers Ltd.