Differences in IgG Antibody Responses following BNT162b2 and mRNA-1273 SARS-CoV-2 Vaccines

  • José G. Montoya
    Dr. Jack S. Remington Laboratory for Specialty Diagnostics, Palo Alto Medical Foundation Research Institute, Palo Alto, California, USA
  • Amy E. Adams
    Palo Alto Foundation Medical Group, Palo Alto, California, USA
  • Valérie Bonetti
    Dr. Jack S. Remington Laboratory for Specialty Diagnostics, Palo Alto Medical Foundation Research Institute, Palo Alto, California, USA
  • Sien Deng
    Center for Health Systems Research, Sutter Health, Palo Alto Medical Foundation Research Institute, Palo Alto, California, USA
  • Nan A. Link
    Palo Alto Foundation Medical Group, Palo Alto, California, USA
  • Suzanne Pertsch
    Palo Alto Foundation Medical Group, Palo Alto, California, USA
  • Kjerstie Olson
    Dr. Jack S. Remington Laboratory for Specialty Diagnostics, Palo Alto Medical Foundation Research Institute, Palo Alto, California, USA
  • Martina Li
    Center for Health Systems Research, Sutter Health, Palo Alto Medical Foundation Research Institute, Palo Alto, California, USA
  • Ellis C. Dillon
    Center for Health Systems Research, Sutter Health, Palo Alto Medical Foundation Research Institute, Palo Alto, California, USA
  • Dominick L. Frosch
    Center for Health Systems Research, Sutter Health, Palo Alto Medical Foundation Research Institute, Palo Alto, California, USA

抄録

<jats:p>SARS-CoV-2 vaccines using the mRNA platform have become one of the most powerful tools to overcome the COVID-19 pandemic. mRNA vaccines enable human cells to produce and present the virus spike protein to their immune system, leading to protection from severe illness. Two mRNA vaccines have been widely implemented, mRNA-1273 (Moderna) and BNT162b2 (Pfizer/BioNTech).</jats:p>

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