Yield of Screening for COVID-19 in Asymptomatic Patients Before Elective or Emergency Surgery Using Chest CT and RT-PCR (SCOUT)
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- Carl A. J. Puylaert
- Department of Radiology and Nuclear Medicine, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Jochem C. G. Scheijmans
- Department of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Alexander B. J. Borgstein
- Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Caroline S. Andeweg
- Department of Surgery, St Jansdal Hospital, Harderwijk, the Netherlands
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- Annemarieke Bartels-Rutten
- Department of Radiology, Netherlands Cancer Institute, Amsterdam, the Netherlands
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- Geerard L. Beets
- Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands
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- Mark I. van Berge Henegouwen
- Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Sicco J. Braak
- Department of Radiology, Hospital Group Twente, Almelo, the Netherlands
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- Roy Couvreur
- Department of Surgery, Haaglanden Medical Center, Den Haag, the Netherlands
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- Freek Daams
- Department of Surgery, Cancer Center Amsterdam UMC, VU University Amsterdam, Amsterdam, the Netherlands
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- Hendrik W. van Es
- Department of Radiology, Sint Antonius Hospital, Nieuwegein, the Netherlands
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- Lotte C. Franken
- Department of Surgery, Flevo Hospital, Almere, the Netherlands
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- Brechtje A. Grotenhuis
- Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands
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- Eduard R. Hendriks
- Department of Surgery, Tergooi Hospitals, Hilversum, the Netherlands
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- Ignace H. J. T. de Hingh
- Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands
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- Fieke Hoeijmakers
- Department of Surgery, Dijklander Hospital, Hoorn, the Netherlands
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- Joris T. ten Holder
- Department of Pulmonary Medicine, Haaglanden Medical Center, Den Haag, the Netherlands
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- Peter M. Huisman
- Department of Radiology, Tergooi Hospitals, Hilversum, the Netherlands
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- Geert Kazemier
- Department of Surgery, Cancer Center Amsterdam UMC, VU University Amsterdam, Amsterdam, the Netherlands
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- Floortje van Kesteren
- Department of Radiology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Jurre van Kesteren
- Department of Surgery, Dijklander Hospital, Hoorn, the Netherlands
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- Kammy Keywani
- Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Sara Z. Kuiper
- Department of Surgery, Maastricht UMC+, Maastricht, the Netherlands
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- Maurits D. J. Lange
- Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands
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- Mark E. Lobatto
- Department of Radiology, Spaarne Gasthuis, Haarlem and Hoofddorp, the Netherlands
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- Arthur W. F. du Mée
- Department of Radiology, Amphia Hospital, Breda, the Netherlands
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- Martijn Poeze
- Department of Surgery, Maastricht UMC+, Maastricht, the Netherlands
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- Elise M. van Praag
- Department of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Jorit van Rossen
- Department of Radiology, Hospital Group Twente, Almelo, the Netherlands
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- Hjalmar C. van Santvoort
- Department of Surgery, Sint Antonius Hospital, Nieuwegein, the Netherlands
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- Wouter J. A. Sedee
- Department of Emergency Medicine, St Jansdal Hospital, Harderwijk, the Netherlands
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- Leonard W. F. Seelen
- Department of Surgery, Sint Antonius Hospital, Nieuwegein, the Netherlands
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- Sarah Sharabiany
- Department of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Nico L. Sosef
- Department of Surgery, Spaarne Gasthuis, Haarlem and Hoofddorp, the Netherlands
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- Marian J. R. Quanjel
- Department of Pulmonary Medicine, Sint Antonius Hospital, Nieuwegein, the Netherlands
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- Jeroen Veltman
- Department of Radiology, Hospital Group Twente, Almelo, the Netherlands
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- Tim Verhagen
- Department of Surgery, Hospital Group Twente, Almelo, the Netherlands
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- Vincent C. J. van de Vlasakker
- Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands
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- Pepijn D. Weeder
- Department of Surgery, Spaarne Gasthuis, Haarlem and Hoofddorp, the Netherlands
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- Jochem R. van Werven
- Department of Radiology, Amphia Hospital, Breda, the Netherlands
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- Nina J. Wesdorp
- Department of Surgery, Cancer Center Amsterdam UMC, VU University Amsterdam, Amsterdam, the Netherlands
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- Susan van Dieren
- Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Alvin X. Han
- Laboratory of Applied Evolutionary Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Colin A. Russell
- Laboratory of Applied Evolutionary Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Menno D. de Jong
- Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Patrick M. M. Bossuyt
- Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Jet M. E. Quarles van Ufford
- Department of Radiology, Haaglanden Medical Center, Den Haag, the Netherlands
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- Mathias W. Prokop
- Department of Radiology, Radboud UMC, Nijmegen, the Netherlands
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- Suzanne S. Gisbertz
- Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Jan M. Prins
- Department of Internal Medicine, Division of Infectious Diseases, Amsterdam Institute for Infection and Immunity (AI&II), Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Marc G. Besselink
- Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Marja A. Boermeester
- Department of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
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- Hester A. Gietema
- Department of Radiology, Maastricht UMC+, Maastricht, the Netherlands.
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- Jaap Stoker
- Department of Radiology and Nuclear Medicine, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
書誌事項
- タイトル別名
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- Multicenter Study
抄録
<jats:sec> <jats:title>Objective:</jats:title> <jats:p>To determine the yield of preoperative screening for COVID-19 with chest CT and RT-PCR in patients without COVID-19 symptoms.</jats:p> </jats:sec> <jats:sec> <jats:title>Summary of Background Data:</jats:title> <jats:p>Many centers are currently screening surgical patients for COVID-19 using either chest CT, RT-PCR or both, due to the risk for worsened surgical outcomes and nosocomial spread. The optimal design and yield of such a strategy are currently unknown.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods:</jats:title> <jats:p>This multicenter study included consecutive adult patients without COVID-19 symptoms who underwent preoperative screening using chest CT and RT-PCR before elective or emergency surgery under general anesthesia.</jats:p> </jats:sec> <jats:sec> <jats:title>Results:</jats:title> <jats:p>A total of 2093 patients without COVID-19 symptoms were included in 14 participating centers; 1224 were screened by CT and RT-PCR and 869 by chest CT only. The positive yield of screening using a combination of chest CT and RT-PCR was 1.5% [95% confidence interval (CI): 0.8–2.1]. Individual yields were 0.7% (95% CI: 0.2–1.1) for chest CT and 1.1% (95% CI: 0.6–1.7) for RT-PCR; the incremental yield of chest CT was 0.4%. In relation to COVID-19 community prevalence, up to ∼6% positive RT-PCR was found for a daily hospital admission rate >1.5 per 100,000 inhabitants, and around 1.0% for lower prevalence.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions:</jats:title> <jats:p>One in every 100 patients without COVID-19 symptoms tested positive for SARS-CoV-2 with RT-PCR; this yield increased in conjunction with community prevalence. The added value of chest CT was limited. Preoperative screening allowed us to take adequate precautions for SARS-CoV-2 positive patients in a surgical population, whereas negative patients needed only routine procedures.</jats:p> </jats:sec>
収録刊行物
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- Annals of Surgery
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Annals of Surgery 272 (6), 919-924, 2020-07-14
Ovid Technologies (Wolters Kluwer Health)
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キーワード
詳細情報 詳細情報について
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- CRID
- 1360298343141470848
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- ISSN
- 15281140
- 00034932
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- データソース種別
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- Crossref