Hybridization-specific chemical reactions to create interstrand crosslinking and threaded structures of nucleic acids

  • Kazumitsu Onizuka
    Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan
  • Yuuhei Yamano
    Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan
  • Ahmed Mostafa Abdelhady
    Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan
  • Fumi Nagatsugi
    Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan

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<jats:p>This review introduces the creation of interstrand crosslinking and threaded structures based on the hybridization-specific chemical reactions and their functions and perspectives in oligonucleotide therapeutics, chemical biology and nanotechnology.</jats:p>

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