Liver organ-on-chip models for toxicity studies and risk assessment

DOI Web Site 1 Citations
  • Taha Messelmani
    Université de Technologie de Compiègne, CNRS, Biomechanics and Bioengineering, Centre de Recherche Royallieu CS 60319, 60203 Compiègne Cedex, France
  • Lisa Morisseau
    Université de Technologie de Compiègne, CNRS, Biomechanics and Bioengineering, Centre de Recherche Royallieu CS 60319, 60203 Compiègne Cedex, France
  • Yasuyuki Sakai
    CNRS IRL 2820, Laboratory for Integrated Micro Mechatronic Systems, Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8505, Japan
  • Cécile Legallais
    Université de Technologie de Compiègne, CNRS, Biomechanics and Bioengineering, Centre de Recherche Royallieu CS 60319, 60203 Compiègne Cedex, France
  • Anne Le Goff
    Université de Technologie de Compiègne, CNRS, Biomechanics and Bioengineering, Centre de Recherche Royallieu CS 60319, 60203 Compiègne Cedex, France
  • Eric Leclerc
    CNRS IRL 2820, Laboratory for Integrated Micro Mechatronic Systems, Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8505, Japan
  • Rachid Jellali
    Université de Technologie de Compiègne, CNRS, Biomechanics and Bioengineering, Centre de Recherche Royallieu CS 60319, 60203 Compiègne Cedex, France

Description

<jats:p>This review provides an overview of liver organ-on-chip (OoC) technology, including the general concept, different approaches and recent advances. A particular focus is given to the use of liver OoC in toxicity studies and risk assessment.</jats:p>

Journal

  • Lab on a Chip

    Lab on a Chip 22 (13), 2423-2450, 2022

    Royal Society of Chemistry (RSC)

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