The Ubiquitous Human Skin Commensal Staphylococcus hominis Protects against Opportunistic Pathogens
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- Morgan M. Severn
- Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA
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- Michael R. Williams
- Department of Dermatology, University of California, San Diego, La Jolla, California, USA
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- Ali Shahbandi
- Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA
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- Zoie L. Bunch
- Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA
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- Laurie M. Lyon
- Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA
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- Amber Nguyen
- Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA
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- Livia S. Zaramela
- Department of Pediatrics, University of California, San Diego, La Jolla, California, USA
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- Daniel A. Todd
- Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA
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- Karsten Zengler
- Department of Pediatrics, University of California, San Diego, La Jolla, California, USA
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- Nadja B. Cech
- Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA
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- Richard L. Gallo
- Department of Dermatology, University of California, San Diego, La Jolla, California, USA
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- Alexander R. Horswill
- Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA
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- Victor J. Torres
- editor
説明
<jats:p> Human skin is home to a variety of commensal bacteria, including many species of coagulase-negative staphylococci (CoNS). While it is well established that the microbiota as a whole maintains skin homeostasis and excludes pathogens (i.e., colonization resistance), relatively little is known about the unique contributions of individual CoNS species to these interactions. <jats:named-content content-type="genus-species">Staphylococcus hominis</jats:named-content> is the second most frequently isolated CoNS from healthy skin, and there is emerging evidence to suggest that it may play an important role in excluding pathogens, including <jats:named-content content-type="genus-species">Staphylococcus aureus</jats:named-content> , from colonizing or infecting the skin. </jats:p>
収録刊行物
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- mBio
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mBio 13 (3), 2022-06-28
American Society for Microbiology
