Modified Drug-Susceptibility Testing and Screening Culture Agar for Colistin-Susceptible <i>Enterobacteriaceae</i> Isolates Harboring a Mobilized Colistin Resistance Gene <i>mcr-9</i>

DOI Web Site 参考文献41件 オープンアクセス
  • Pegah Kananizadeh
    Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan
  • Tatsuya Tada
    Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan
  • Satoshi Oshiro
    Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan
  • Tomomi Hishinuma
    Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan
  • Mari Tohya
    Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan
  • Yuki Uehara
    Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan
  • Yumi Kumagai
    Department of Host Defense and Biochemical Research, Juntendo University School of Medicine, Tokyo, Japan
  • Isao Nagaoka
    Faculty of Medical Science, Juntendo University, Chiba, Japan
  • Kanako Nishi
    Department of Chemistry and Biotechnology, Kagoshima University, Kagoshima, Japan
  • Masahito Hashimoto
    Department of Chemistry and Biotechnology, Kagoshima University, Kagoshima, Japan
  • Shin Watanabe
    Department of Microbiome, Juntendo University School of Medicine, Tokyo, Japan
  • Teruo Kirikae
    Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan
  • Nathan A. Ledeboer
    editor

抄録

<jats:p> Three isolates of the <jats:named-content content-type="genus-species">Enterobacter cloacae</jats:named-content> complex harboring <jats:italic>mcr-9</jats:italic> , a member of the colistin resistance <jats:italic>mcr</jats:italic> gene family encoded on plasmids, were susceptible to colistin, with MICs of 0.125 to 0.5 μg/mL in standard broth microdilution (BMD) tests using cation-adjusted Mueller-Hinton broth (CA-MHB) in accordance with European Committee on Antimicrobial Susceptibility Testing guidelines. In contrast, their MICs for colistin were significantly higher (4 to 128 μg/mL) when BMD tests were performed using brain-heart infusion (BHI) medium, Luria-Bertani (LB) broth, tryptic soy broth (TSB), or CA-MHB supplemented with casein, tryptonen or peptone. </jats:p>

収録刊行物

参考文献 (41)*注記

もっと見る

関連プロジェクト

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ