DNA-functionalized colloidal crystals for macromolecular encapsulation

  • Maasa Yokomori
    Center for Integrated Research of Future Electronics (CIRFE), Institute of Materials and Systems for Sustainability (IMaSS), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan
  • Hayato Suzuki
    Plant Gene Regulation Research Group, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, 305-8566, Japan
  • Akiyoshi Nakamura
    Plant Gene Regulation Research Group, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, 305-8566, Japan
  • Shigeo S. Sugano
    Plant Gene Regulation Research Group, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, 305-8566, Japan
  • Miho Tagawa
    Center for Integrated Research of Future Electronics (CIRFE), Institute of Materials and Systems for Sustainability (IMaSS), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan

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Description

<jats:p>Metal-DNA hybrid crystals were demonstrated to be applied to encapsulate macromolecules such as streptavidin protein, Qdot, or Cas9 endonuclease by harnessing the hollow spaces in the crystal lattices and their affinities for the target molecules.</jats:p>

Journal

  • Soft Matter

    Soft Matter 18 (36), 6954-6964, 2022

    Royal Society of Chemistry (RSC)

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