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- Cai-Ming Xu
- Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, Liaoning, China; Institute (College) of Intergrative Medicine, Dalian Medical University, Dalian 116044, Liaoning, China
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- Ya-Lan Luo
- Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, Liaoning, China; Institute (College) of Intergrative Medicine, Dalian Medical University, Dalian 116044, Liaoning, China
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- Shuai Li
- Department of Pediatric Orthopedics, Qingdao Women and Children’s Hospital, Qingdao 266035, Shandong, China
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- Zhao-Xia Li
- Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, Liaoning, China; Institute (College) of Intergrative Medicine, Dalian Medical University, Dalian 116044, Liaoning, China
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- Liu Jiang
- Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, Liaoning, China; Institute (College) of Intergrative Medicine, Dalian Medical University, Dalian 116044, Liaoning, China
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- Gui-Xin Zhang
- Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, Liaoning, China; Institute (College) of Intergrative Medicine, Dalian Medical University, Dalian 116044, Liaoning, China
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- Lawrence Owusu
- Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, Liaoning, China; Institute (College) of Intergrative Medicine, Dalian Medical University, Dalian 116044, Liaoning, China
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- Hai-Long Chen
- Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, Liaoning, China; Institute (College) of Intergrative Medicine, Dalian Medical University, Dalian 116044, Liaoning, China
抄録
<jats:title>Abstract</jats:title> <jats:p>Neuron-specific enolase (NSE), also known as gamma (γ) enolase or enolase-2 (Eno2), is a form of glycolytic enolase isozyme and is considered a multifunctional protein. NSE is mainly expressed in the cytoplasm of neurons and neuroendocrine cells, especially in those of the amine precursor uptake and decarboxylation (APUD) lineage such as pituitary, thyroid, pancreas, intestine and lung. In addition to its well-established glycolysis function in the cytoplasm, changes in cell localization and differential expression of NSE are also associated with several pathologies such as infection, inflammation, autoimmune diseases and cancer. This article mainly discusses the role and diagnostic potential of NSE in some lung diseases.</jats:p>
収録刊行物
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- Bioscience Reports
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Bioscience Reports 39 (11), 2019-11
Portland Press Ltd.