Distinctive Cortical Articulatory Representation in Cleft Lip and Palate: A Preliminary Functional Magnetic Resonance Imaging Study
-
- Hideo Shinagawa
- Maxillofacial Orthognathics, Tokyo Medical and Dental University, and Tokyo Metropolitan Institute of Gerontology, both in Tokyo, Japan.
-
- Takashi Ono
- Maxillofacial Orthognathics, Tokyo Medical and Dental University, Tokyo, Japan.
-
- Ei-ichi Honda
- Oral/Maxillofacial Radiology, Tokyo Medical and Dental University, Tokyo, Japan, and Oral/Maxillofacial Radiology, Graduate School, The University of Tokushima, Tokushima, Japan.
-
- Tohru Kurabayashi
- Oral/Maxillofacial Radiology, Tokyo Medical and Dental University, Tokyo, Japan.
-
- Atsushi Iriki
- Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
-
- Kimie Ohyama
- Maxillofacial Orthognathics, Tokyo Medical and Dental University, Tokyo, Japan.
抄録
<jats:sec><jats:title>Objective:</jats:title><jats:p>To investigate cortical representation of articulation of the bilabial plosive in patients with cleft lip and palate.</jats:p></jats:sec><jats:sec><jats:title>Design:</jats:title><jats:p>We examined cortical representation for /pa/-articulation in cleft lip and palate patients using blood oxygenation level–dependent functional magnetic resonance imaging.</jats:p></jats:sec><jats:sec><jats:title>Subjects:</jats:title><jats:p>Data from four postsurgical adult cleft lip and palate patients were compared with those from six healthy volunteers.</jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p>Activation foci were found in the bilateral primary sensorimotor cortex in all cleft lip and palate patients, as in the controls. The sensorimotor cortex ipsilateral to the side of cleft lip and palate showed greater activation in unilateral cleft lip and palate patients, whereas the sensorimotor cortex contralateral to the side on which cheiloplasty had been performed earlier showed greater activation in a bilateral cleft lip and palate patient.</jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p>The results suggest that there may be an ipsilateral dominance in cortical representation during bilabial articulation to the side of the cleft in the upper lip.</jats:p></jats:sec>
収録刊行物
-
- The Cleft Palate-Craniofacial Journal
-
The Cleft Palate-Craniofacial Journal 43 (5), 620-624, 2006-09
SAGE Publications
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1360298760524151040
-
- DOI
- 10.1597/05-027
-
- ISSN
- 15451569
- 10556656
-
- データソース種別
-
- Crossref