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- Carolina X Sandler
- The Kirby Institute, UNSW Sydney, New South Wales, Australia
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- Vegard B B Wyller
- Department of Pediatrics and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway
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- Rona Moss-Morris
- Health Psychology, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom
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- Dedra Buchwald
- Institute for Research and Education to Advance Community Health, Washington State University, Seattle, Washington, USA
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- Esther Crawley
- Bristol Medical School, University of Bristol. Bristol. Centre for Academic Child Health, Bristol, United Kingdom
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- Jeannine Hautvast
- Department of Primary and Community Care, Radboud University Medical Center, Nijmegen, Nijmegen, Netherlands
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- Ben Z Katz
- Northwestern University Feinberg School of Medicine, Chicago, Department of Pediatrics, Chicago, Illinois, USA
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- Hans Knoop
- Department of Medical Psychology, Amsterdam University Medical Centers, Amsterdam Public Health Research Institute, University of Amsterdam, Amsterdam, Netherlands
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- Paul Little
- Primary Care Research Centre, Primary Care Public Health and Medical Education Unit, Faculty of Medicine, University of Southampton, United Kingdom
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- Renee Taylor
- College of Applied Health Sciences, University of Illinois at Chicago, Chicago, Illinois, USA
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- Knut-Arne Wensaas
- Research Unit for General Practice, NORCE Norwegian Research Centre, Bergen, Norway
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- Andrew R Lloyd
- The Kirby Institute, UNSW Sydney, New South Wales, Australia
抄録
<jats:title>Abstract</jats:title> <jats:p>Fatigue is a dominant feature of both acute and convalescent coronavirus disease 2019 (COVID-19) (sometimes termed “long-COVID”), with up to 46% of patients reporting fatigue that lasts from weeks to months. The investigators of the international Collaborative on Fatigue Following Infection (COFFI) conducted a systematic review of post-COVID fatigue and a narrative review on fatigue after other infections, and made recommendations for clinical and research approaches to assessing fatigue after COVID-19.</jats:p> <jats:p>In the majority of COVID-19 cohort studies, persistent fatigue was reported by a significant minority of patients, ranging from 13% to 33% at 16–20 weeks post-symptom onset. Data from the prospective cohort studies in COFFI and others indicate that fatigue is also a prevalent outcome from many acute systemic infections, notably infectious mononucleosis, with a case rate for clinically significant Post-infective fatigue after exclusion of recognized medical and psychiatric causes, ranging from 10%–35% at 6 months.</jats:p> <jats:p>To better characterize post-COVID fatigue, the COFFI investigators recommend the following: application of validated screening questionnaires for case detection; standardized interviews encompassing fatigue, mood, and other symptoms; and investigative approaches to identify end-organ damage and mental health conditions.</jats:p>
収録刊行物
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- Open Forum Infectious Diseases
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Open Forum Infectious Diseases 8 (10), ofab440-, 2021-09-09
Oxford University Press (OUP)