Chemically and Biologically Engineered Bacteria‐Based Delivery Systems for Emerging Diagnosis and Advanced Therapy
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- Zhaoting Li
- Pharmaceutical Sciences Division School of Pharmacy Wisconsin Center for NanoBioSystems Carbone Cancer Center School of Medicine and Public Health University of Wisconsin Madison (UW‐Madison) Madison Wisconsin 53705 USA
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- Yixin Wang
- Pharmaceutical Sciences Division School of Pharmacy Wisconsin Center for NanoBioSystems Carbone Cancer Center School of Medicine and Public Health University of Wisconsin Madison (UW‐Madison) Madison Wisconsin 53705 USA
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- Jun Liu
- Pharmaceutical Sciences Division School of Pharmacy Wisconsin Center for NanoBioSystems Carbone Cancer Center School of Medicine and Public Health University of Wisconsin Madison (UW‐Madison) Madison Wisconsin 53705 USA
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- Piper Rawding
- Pharmaceutical Sciences Division School of Pharmacy Wisconsin Center for NanoBioSystems Carbone Cancer Center School of Medicine and Public Health University of Wisconsin Madison (UW‐Madison) Madison Wisconsin 53705 USA
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- Jiyoon Bu
- Pharmaceutical Sciences Division School of Pharmacy Wisconsin Center for NanoBioSystems Carbone Cancer Center School of Medicine and Public Health University of Wisconsin Madison (UW‐Madison) Madison Wisconsin 53705 USA
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- Seungpyo Hong
- Pharmaceutical Sciences Division School of Pharmacy Wisconsin Center for NanoBioSystems Carbone Cancer Center School of Medicine and Public Health University of Wisconsin Madison (UW‐Madison) Madison Wisconsin 53705 USA
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- Quanyin Hu
- Pharmaceutical Sciences Division School of Pharmacy Wisconsin Center for NanoBioSystems Carbone Cancer Center School of Medicine and Public Health University of Wisconsin Madison (UW‐Madison) Madison Wisconsin 53705 USA
説明
<jats:title>Abstract</jats:title><jats:p>Bacteria are one of the main groups of organisms, which dynamically and closely participate in human health and disease development. With the integration of chemical biotechnology, bacteria have been utilized as an emerging delivery system for various biomedical applications. Given the unique features of bacteria such as their intrinsic biocompatibility and motility, bacteria‐based delivery systems have drawn wide interest in the diagnosis and treatment of various diseases, including cancer, infectious diseases, kidney failure, and hyperammonemia. Notably, at the interface of chemical biotechnology and bacteria, many research opportunities have been initiated, opening a promising frontier in biomedical application. Herein, the current synergy of chemical biotechnology and bacteria, the design principles for bacteria‐based delivery systems, the microbial modulation, and the clinical translation are reviewed, with a special focus on the emerging advances in diagnosis and therapy.</jats:p>
収録刊行物
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- Advanced Materials
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Advanced Materials 33 (38), 2021-08-04
Wiley