Near‐Infrared Windows I and II Phosphors for Theranostic Applications: Spectroscopy, Bioimaging, and Light‐Emitting Diode Photobiomodulation

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  • Wen‐Tse Huang
    Department of Chemistry and Advanced Research Center of Green Materials Science and Technology National Taiwan University Taipei 106 Taiwan
  • Veeramani Rajendran
    Department of Mechanical Engineering and Graduate Institute of Manufacturing Technology National Taipei University of Technology Taipei 106 Taiwan
  • Ming‐Hsien Chan
    Genomics Research Center Academia Sinica Taipei 106 Taiwan
  • Michael Hsiao
    Genomics Research Center Academia Sinica Taipei 106 Taiwan
  • Ho Chang
    Department of Mechanical Engineering and Graduate Institute of Manufacturing Technology National Taipei University of Technology Taipei 106 Taiwan
  • Ru‐Shi Liu
    Department of Chemistry and Advanced Research Center of Green Materials Science and Technology National Taiwan University Taipei 106 Taiwan

書誌事項

公開日
2022-12-19
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/adom.202202061
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>The importance and practicality of near‐infrared (NIR) light for the biomedical field has attached importance to the academe and industry with the development of technology. Luminescent materials with different doping strategies are promising candidates for covering near‐infrared biological windows from 700 nm to 1 700 nm. The relationship between NIR light, nanophosphors, and biological tissue towards the function of diagnostic and therapy in different NIR windows is explored clearly, which corresponds to diffuse reflection spectroscopy with bioimaging and light‐emitting diode (LED) photobiomodulation. The diseases can be monitored with specific chromophore absorption under the NIR light source, which also can be traced to the dynamic change of the biological environment by luminescent materials. Especially in brain diseases, cytochrome <jats:italic>c</jats:italic> oxidase in mitochondria as the crucial photoreceptor can be activated under NIR irradiation to achieve the non‐invasive treatment of neuron protection and recovery. NIR light attributed to LED or nanophosphors show the potential of theranostic approaches in biomedical technology. Cr<jats:sup>3+</jats:sup>‐ and Ni<jats:sup>2+</jats:sup>‐activated phosphors covering NIR windows I and II are presented with optical properties to explore the feasibility and practicability of non‐invasive precise medical treatment in the future.</jats:p>

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