GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

DOI Web Site 被引用文献1件
  • Alexessander Couto Alves
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • N. Maneka G. De Silva
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Ville Karhunen
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Ulla Sovio
    Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK.
  • Shikta Das
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • H. Rob Taal
    The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
  • Nicole M. Warrington
    Division of Obstetrics and Gynaecology, The University of Western Australia, Perth, Western Australia, Australia.
  • Alexandra M. Lewin
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Marika Kaakinen
    Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK.
  • Diana L. Cousminer
    Division of Human Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA.
  • Elisabeth Thiering
    Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich Neuherberg, Germany.
  • Nicholas J. Timpson
    MRC Integrative Epidemiology Unit at the University of Bristol and NIHR Bristol Biomedical Research Center, Bristol, UK.
  • Tom A. Bond
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Estelle Lowry
    Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.
  • Christopher D. Brown
    Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Xavier Estivill
    Genomics and Disease Group, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), Barcelona, Catalonia, Spain.
  • Virpi Lindi
    Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland.
  • Jonathan P. Bradfield
    Center for Applied Genomics, Abramson Research Center, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA.
  • Frank Geller
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Doug Speed
    Aarhus Institute of Advanced Studies (AIAS), Aarhus University, Aarhus, Denmark.
  • Lachlan J. M. Coin
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Marie Loh
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Sheila J. Barton
    MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.
  • Lawrence J. Beilin
    Medical School, Royal Perth Hospital, University of Western Australia, Perth, Western Australia, Australia.
  • Hans Bisgaard
    COPSAC, The Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Klaus Bønnelykke
    COPSAC, The Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Rohia Alili
    CRNH Ile de France, Hôpital Pitié-Salpêtrière, Paris, France.
  • Ida J. Hatoum
    CRNH Ile de France, Hôpital Pitié-Salpêtrière, Paris, France.
  • Katharina Schramm
    Institute of Human Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.
  • Rufus Cartwright
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Marie-Aline Charles
    Inserm, UMR 1153 (CRESS), Paris Descartes University, Villejuif, Paris, France.
  • Vincenzo Salerno
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Karine Clément
    CRNH Ile de France, Hôpital Pitié-Salpêtrière, Paris, France.
  • Annique A. J. Claringbould
    University Medical Centre Groningen, Department of Genetics, Antonius Deusinglaan 1, 9713 AV Groningen, Netherlands.
  • Cornelia M. van Duijn
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
  • Elena Moltchanova
    Department of Mathematics and Statistics, University of Canterbury, Christchurch, New Zealand.
  • Johan G. Eriksson
    Department of General Practice and Primary Health Care, University of Helsinki, and Helsinki University Hospital, Helsinki, Finland.
  • Cathy Elks
    MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.
  • Bjarke Feenstra
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Claudia Flexeder
    Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich Neuherberg, Germany.
  • Stephen Franks
    Institute for Reproductive and Developmental Biology, Imperial College London, London, UK.
  • Timothy M. Frayling
    Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.
  • Rachel M. Freathy
    Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.
  • Paul Elliott
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Elisabeth Widén
    Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
  • Hakon Hakonarson
    Division of Human Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA.
  • Andrew T. Hattersley
    Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.
  • Alina Rodriguez
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Marco Banterle
    Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
  • Joachim Heinrich
    Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich Neuherberg, Germany.
  • Barbara Heude
    Inserm, UMR 1153 (CRESS), Paris Descartes University, Villejuif, Paris, France.
  • John W. Holloway
    Human Genetics and Medical Genomics, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Albert Hofman
    The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
  • Elina Hyppönen
    South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
  • Hazel Inskip
    MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.
  • Lee M. Kaplan
    Obesity, Metabolism, and Nutrition Institute and Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Asa K. Hedman
    Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Esa Läärä
    Research Unit of Mathematical Sciences, University of Oulu, Oulu, Finland.
  • Holger Prokisch
    Institute of Human Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.
  • Harald Grallert
    Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Timo A. Lakka
    Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland.
  • Debbie A. Lawlor
    MRC Integrative Epidemiology Unit at the University of Bristol and NIHR Bristol Biomedical Research Center, Bristol, UK.
  • Mads Melbye
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Tarunveer S. Ahluwalia
    COPSAC, The Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Marcella Marinelli
    Hospital del Mar Medical Research Institute (IMIM), Barcelona, Catalonia, Spain.
  • Iona Y. Millwood
    Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), University of Oxford, Old Road Campus, Oxford, UK.
  • Lyle J. Palmer
    School of Public Health and Robinson Research Institute, University of Adelaide, Adelaide, Australia.
  • Craig E. Pennell
    Division of Obstetrics and Gynaecology, The University of Western Australia, Perth, Western Australia, Australia.
  • John R. Perry
    MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.
  • Susan M. Ring
    MRC Integrative Epidemiology Unit at the University of Bristol and NIHR Bristol Biomedical Research Center, Bristol, UK.
  • Markku J. Savolainen
    Division of Internal Medicine, and Biocenter of Oulu, Faculty of Medicine, Oulu University, Oulu, Finland.
  • Fernando Rivadeneira
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
  • Marie Standl
    Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich Neuherberg, Germany.
  • Jordi Sunyer
    Pompeu Fabra University (UPF), Barcelona, Catalonia, Spain.
  • Carla M. T. Tiesler
    Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich Neuherberg, Germany.
  • Andre G. Uitterlinden
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
  • William Schierding
    Liggins Institute, University of Auckland, Auckland, New Zealand.
  • Justin M. O’Sullivan
    Liggins Institute, University of Auckland, Auckland, New Zealand.
  • Inga Prokopenko
    Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK.
  • Karl-Heinz Herzig
    Biocenter Oulu, University of Oulu, Oulu, Finland.
  • George Davey Smith
    MRC Integrative Epidemiology Unit at the University of Bristol and NIHR Bristol Biomedical Research Center, Bristol, UK.
  • Paul O'Reilly
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Janine F. Felix
    The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
  • Jessica L. Buxton
    School of Life Sciences, Pharmacy and Chemistry, Kingston University, Kingston upon Thames, UK.
  • Alexandra I. F. Blakemore
    Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.
  • Ken K. Ong
    MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.
  • Vincent W. V. Jaddoe
    The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
  • Struan F. A. Grant
    Division of Human Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA.
  • Sylvain Sebert
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Mark I. McCarthy
    Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Marjo-Riitta Järvelin
    Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.

抄録

<jats:p>Longitudinal data find a new variant controlling BMI in infancy and reveal genetic differences between infant and adult BMI.</jats:p>

収録刊行物

  • Science Advances

    Science Advances 5 (9), eaaw3095-, 2019-09-06

    American Association for the Advancement of Science (AAAS)

被引用文献 (1)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ