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  • Processing and characterization of supercritical CO<sub>2</sub>batch foamed poly(lactic acid)/poly(ethylene glycol) scaffold for tissue engineering application

    • Wenhao Zhang
      The Key Laboratory of Polymer Processing Engineering of Ministry of Education National Engineering Research Center of Novel Equipment for Polymer Processing South China University of Technology Guangzhou 510640 China
    • Binyi Chen
      The Key Laboratory of Polymer Processing Engineering of Ministry of Education National Engineering Research Center of Novel Equipment for Polymer Processing South China University of Technology Guangzhou 510640 China
    • Haibin Zhao
      The Key Laboratory of Polymer Processing Engineering of Ministry of Education National Engineering Research Center of Novel Equipment for Polymer Processing South China University of Technology Guangzhou 510640 China
    • Peng Yu
      The Key Laboratory of Polymer Processing Engineering of Ministry of Education National Engineering Research Center of Novel Equipment for Polymer Processing South China University of Technology Guangzhou 510640 China
    • Dajiong Fu
      The Key Laboratory of Polymer Processing Engineering of Ministry of Education National Engineering Research Center of Novel Equipment for Polymer Processing South China University of Technology Guangzhou 510640 China
    • Jinsong Wen
      The Key Laboratory of Polymer Processing Engineering of Ministry of Education National Engineering Research Center of Novel Equipment for Polymer Processing South China University of Technology Guangzhou 510640 China
    • Xiangfang Peng
      The Key Laboratory of Polymer Processing Engineering of Ministry of Education National Engineering Research Center of Novel Equipment for Polymer Processing South China University of Technology Guangzhou 510640 China

    書誌事項

    公開日
    2013-06-08
    権利情報
    • http://onlinelibrary.wiley.com/termsAndConditions#vor
    DOI
    • 10.1002/app.39523
    公開者
    Wiley

    この論文をさがす

    説明

    <jats:title>ABSTRACT</jats:title><jats:p>Both poly(lactic acid) (PLA) and poly(ethylene glycol) (PEG) are biodegradable polymers, blending PLA with PEG is expected to toughen PLA matrix while maintaining its biodegradability. In this study, PLA/PEG blends in different ratios were prepared through triple‐screw extruder, and the foaming behavior was investigated using supercritical carbon dioxide as physical blowing agent. The mechanical, thermal, rheological properties, and crystallization behavior were also studied. By the incorporation of PEG, the impact strength of the PLA/PEG blends improved by 98% with the specimens fractured in a ductile mode. The crystallization process of the blends was accelerated, and the crystallinity was significantly increased to 45.1%. The viscoelasticity of the PLA/PEG matrix was weakened, and the cells tended to break at the cell wall during cell expansion; thus, a highly interconnected structure with a maximum porosity of 82.3% was obtained. Moreover, the PLA/PEG blends exhibited higher cell densities and smaller cell size, compared to their neat counterparts. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 3066–3073, 2013</jats:p>

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