Role of omega‐6 and omega‐3 fatty acids in fetal programming

DOI Web Site Web Site Web Site 1 Citations
  • Nirajan Shrestha
    School of Medical Science Griffith University Southport Qld Australia
  • Simone L. Sleep
    School of Medical Science Griffith University Southport Qld Australia
  • James S.M. Cuffe
    School of Medical Science Griffith University Southport Qld Australia
  • Olivia J. Holland
    School of Medical Science Griffith University Southport Qld Australia
  • Anthony V. Perkins
    School of Medical Science Griffith University Southport Qld Australia
  • Suk Yu Yau
    Department of Rehabilitation Sciences The Hong Kong Polytechnic University Hong Kong Hong Kong
  • Andrew J. McAinch
    Institute for Health and Sport Victoria University Melbourne Vic. Australia
  • Deanne H. Hryciw
    Institute for Health and Sport Victoria University Melbourne Vic. Australia

Description

<jats:title>Abstract</jats:title><jats:p>Maternal nutrition plays a critical role in fetal development and can influence adult onset of disease. Linoleic acid (LA) and alpha‐linolenic acid (ALA) are major omega‐6 (n‐6) and n‐3 polyunsaturated fatty acids (PUFA), respectively, that are essential in our diet. LA and ALA are critical for the development of the fetal neurological and immune systems. However, in recent years, the consumption of n‐6 PUFA has increased gradually worldwide, and elevated n‐6 PUFA consumption may be harmful to human health. Consumption of diets with high levels of n‐6 PUFA before or during pregnancy may have detrimental effects on fetal development and may influence overall health of offspring in adulthood. This review discusses the role of n‐6 PUFA in fetal programming, the importance of a balance between n‐6 and n‐3 PUFAs in the maternal diet, and the need of further animal models and human studies that critically evaluate both n‐6 and n‐3 PUFA contents in diets.</jats:p>

Journal

Citations (1)*help

See more

Report a problem

Back to top