Use of chiral auxiliaries in the asymmetric synthesis of biologically active compounds: A review
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- Gaspar Diaz‐Muñoz
- Department of Chemistry Universidade Federal de Minas Gerais Belo Horizonte Brazil
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- Izabel Luzia Miranda
- Department of Chemistry Universidade Federal de Minas Gerais Belo Horizonte Brazil
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- Suélen Karine Sartori
- Department of Chemistry Universidade Federal de Minas Gerais Belo Horizonte Brazil
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- Daniele Cristina de Rezende
- Department of Chemistry Universidade Federal de Minas Gerais Belo Horizonte Brazil
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- Marisa Alves Nogueira Diaz
- Department of Biochemistry and Molecular Biology Universidade Federal de Viçosa Viçosa Brazil
説明
<jats:title>Abstract</jats:title><jats:p>This review article describes the use of some of the most popular chiral auxiliaries in the asymmetric synthesis of biologically active compounds. Chiral auxiliaries derived from naturally occurring compounds, such as amino acids, carbohydrates, and terpenes, are considered essential tools for the construction of highly complex molecules. We highlight the auxiliaries of Evans, Corey, Yamada, Enders, Oppolzer, and Kunz, which led to remarkable progress in asymmetric synthesis in the last decades and continue to bring advances until the present day.</jats:p>
収録刊行物
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- Chirality
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Chirality 31 (10), 776-812, 2019-08-16
Wiley
