Changes in the fecal gut microbiome of home healthcare patients with disabilities through consumption of malted rice amazake

  • Suzumi Kageyama
    Graduate School of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan
  • Rikako Inoue
    Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan
  • Jonguk Park
    Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan
  • Koji Hosomi
    Microbial Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan
  • Hitomi Yumioka
    Microbial Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan
  • Tomo Suka
    Kishu Rehabilitation Visiting Care Station, Wakayama, Japan
  • Kazuaki Teramoto
    Kishu Rehabilitation Visiting Care Station, Wakayama, Japan
  • A. Yasmin Syauki
    Graduate School of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan
  • Miki Doi
    Graduate School of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan
  • Haruka Sakaue
    Graduate School of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan
  • Miyuu Miyake
    Graduate School of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan
  • Kenji Mizuguchi
    Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan
  • Jun Kunisawa
    Microbial Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan
  • Yasuyuki Irie
    Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan

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<jats:p> The consumption of malted rice amazake (MR-Amazake) showed significant changes in the gut microbiome according to principal coordinate analysis in some home healthcare patients with disabilities, including those with severe motor and intellectual disabilities. After discontinuation of intake, the gut microbiome returned to its original state. This is the first pilot study to examine both the changes in the gut microbiome and their sustainability after MR-Amazake intake. </jats:p>

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