ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease

DOI Web Site 2 Citations
  • Philip O. Katz
    Department of Medicine, Division of Gastroenterology and Hepatology, Jay Monahan Center for Gastrointestinal Health, Weill Cornell Medicine, New York, New York, USA;
  • Kerry B. Dunbar
    Department of Medicine, University of Texas Southwestern Medical Center, Dallas VA Medical Center, Dallas, Texas, USA;
  • Felice H. Schnoll-Sussman
    Department of Medicine, Division of Gastroenterology and Hepatology, Jay Monahan Center for Gastrointestinal Health, Weill Cornell Medicine, New York, New York, USA;
  • Katarina B. Greer
    Department of Medicine, Case Western Reserve University School of Medicine, Cleveland Louis Stokes VA Medical Center, Cleveland, Ohio, USA;
  • Rena Yadlapati
    Division of Gastroenterology, Department of Medicine, University of California SanDiego, La Jolla, California, USA;
  • Stuart Jon Spechler
    Division of Gastroenterology, Baylor University Medical Center at Dallas, Dallas, Texas, USA;

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<jats:p>Gastroesophageal reflux disease (GERD) continues to be among the most common diseases seen by gastroenterologists, surgeons, and primary care physicians. Our understanding of the varied presentations of GERD, enhancements in diagnostic testing, and approach to patient management have evolved. During this time, scrutiny of proton pump inhibitors (PPIs) has increased considerably. Although PPIs remain the medical treatment of choice for GERD, multiple publications have raised questions about adverse events, raising doubts about the safety of long-term use and increasing concern about overprescribing of PPIs. New data regarding the potential for surgical and endoscopic interventions have emerged. In this new document, we provide updated, evidence-based recommendations and practical guidance for the evaluation and management of GERD, including pharmacologic, lifestyle, surgical, and endoscopic management. The Grading of Recommendations, Assessment, Development, and Evaluation system was used to evaluate the evidence and the strength of recommendations. Key concepts and suggestions that as of this writing do not have sufficient evidence to grade are also provided.</jats:p>

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