Developing a transwell millifluidic device for studying blood–brain barrier endothelium
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- Ian C. Harding
- Department of Bioengineering, Northeastern University, Boston, MA, USA
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- Nicholas R. O'Hare
- Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, 129 Interdisciplinary Science and Engineering Complex, Boston, MA, 02115, USA
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- Mark Vigliotti
- Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, 129 Interdisciplinary Science and Engineering Complex, Boston, MA, 02115, USA
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- Alex Caraballo
- Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, 129 Interdisciplinary Science and Engineering Complex, Boston, MA, 02115, USA
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- Claire I. Lee
- Department of Bioengineering, Northeastern University, Boston, MA, USA
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- Karina Millican
- Department of Bioengineering, Northeastern University, Boston, MA, USA
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- Ira M. Herman
- Department of Developmental, Molecular, and Chemical Biology, Tufts School of Graduate Biomedical Sciences, Boston, MA, USA
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- Eno E. Ebong
- Department of Bioengineering, Northeastern University, Boston, MA, USA
説明
<jats:p>To investigate blood–brain barrier function, a millifluidic device was developed for endothelium, astrocyte, and pericyte co-culture on transwell inserts, fluid flow incorporation, and immunocytochemical, western blot, and permeability assays.</jats:p>
収録刊行物
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- Lab on a Chip
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Lab on a Chip 22 (23), 4603-4620, 2022
Royal Society of Chemistry (RSC)
