Concurrent intraventricular intracranial myxoid mesenchymal tumor and ependymoma in a long‐term Ewing sarcoma survivor
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- Adam S. Levy
- Department of Neurosurgery University of Miami Miller School of Medicine Miami Florida USA
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- Ana Sakellakis
- Department of Neurosurgery University of Miami Miller School of Medicine Miami Florida USA
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- Evan Luther
- Department of Neurosurgery University of Miami Miller School of Medicine Miami Florida USA
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- Alexis A. Morell
- Department of Neurosurgery University of Miami Miller School of Medicine Miami Florida USA
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- Andrew Rosenberg
- Department of Pathology University of Miami Health System Miami Florida USA
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- Ali G. Saad
- Department of Pathology University of Miami Health System Miami Florida USA
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- Michael Ivan
- Department of Neurosurgery University of Miami Miller School of Medicine Miami Florida USA
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- Ricardo J. Komotar
- Department of Neurosurgery University of Miami Miller School of Medicine Miami Florida USA
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説明
<jats:p>Intracranial myxoid mesenchymal tumor, FET::CREB fusion positive is a rare, recently described central nervous system neoplasm. It is characterized by <jats:italic>EWSR1::CREB</jats:italic> family transcription factor fusion, typically arises in children and adolescents, and is locally aggressive even after gross total resection. Currently, there are little data available to guide management and gauge long‐term prognosis. Furthermore, there have been no reports of these lesions occurring simultaneously with other intracranial neoplasms or in patients with a history of malignancy. Here we describe the first case of a very unusual patient with intracranial myxoid mesenchymal tumor of the right lateral ventricle with a concurrent fourth ventricular ependymoma who had a remote history of Ewing sarcoma of the right fibula.</jats:p>
収録刊行物
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- Neuropathology
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Neuropathology 42 (6), 534-539, 2022-06-23
Wiley
