Formation of Planar Bilayer Membranes on Solid Supports Using Peptide Gemini Surfactants

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<jats:title>Abstract</jats:title> <jats:p>Peptide-based gemini surfactants, called PG-surfactants, consisting of a tri- or tetra-Asp peptide core and acetylated dodecylamine-conjugated Cys residues at both the N- and C-terminal ends (D3C12 and D4C12), form a stable planar bilayer membrane on a solid support. From the DLS and TEM analyses, D3C12 and D4C12 have a tendency to form bilayer morphologies in a buffer solution, which reflects their tendency to form a stable planar bilayer membrane.</jats:p>

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  • Chemistry Letters

    Chemistry Letters 41 (11), 1430-1432, 2012-10-27

    Oxford University Press (OUP)

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