Marginal structural models for estimating principal stratum direct effects under the monotonicity assumption
抄録
<jats:title>Abstract</jats:title><jats:p>In epidemiological and clinical research, investigators are frequently interested in estimating the direct effect of a treatment on an outcome that is not relayed by intermediate variables. In 2009, VanderWeele presented marginal structural models (MSMs) for estimating direct effects based on interventions on the mediator. This paper focuses on direct effects based on principal stratification, i.e. principal stratum direct effects (PSDEs), which are causal effects within latent subgroups of subjects where the mediator is constant, regardless of the exposure status. We propose MSMs for estimating PSDEs. We demonstrate that the PSDE can be estimated readily using MSMs under the monotonicity assumption.</jats:p>
収録刊行物
-
- Biometrical Journal
-
Biometrical Journal 53 (6), 1025-1034, 2011-10-21
Wiley
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1360567179911631360
-
- ISSN
- 15214036
- 03233847
-
- データソース種別
-
- Crossref
- KAKEN